Nathan Jones enjoyed his first victory as Southampton head coach in the EFL Cup last week, with the Saints recording a 2-1 win over Lincoln City to advance to the quarter-finals of the competition.
Southampton have lost each of their last three in the Premier League, though, including a 3-1 defeat to Liverpool in their last game before the break for the World Cup.
Brighton, meanwhile, suffered a surprise defeat to Charlton Athletic in the EFL Cup on Wednesday night, losing on penalties to the League One outfit following a 0-0 draw.
The Seagulls also lost their last Premier League game at home to Aston Villa, but a successful start to the season has left them in seventh position in the table, boasting 21 points from their opening 14 matches.
Brighton are actually above Chelsea in the table and just one point behind Liverpool, while they have scored 23 times in England’s top flight during the 2022-23 campaign.
Brighton have some tough games to come in England’s top flight, with two of their next three matches against Arsenal and Liverpool, which adds to the importance of the fixture with the struggling Saints.
Southampton will again be without the services of Tino Livramento and Juan Larios through injury, while Theo Walcott is a doubt with the problem that forced him off the field against Lincoln last time out.
Romeo Lavia also faces a late fitness test on a thigh problem.
Che Adams scored twice against Lincoln and is again expected to lead the line on Monday, while Adam Armstrong could also retain his spot in the final third of the field for the hosts.
As for Brighton, World Cup winner Alexis Mac Allister is missing following his involvement in last weekend’s final between Argentina and France.
Danny Welbeck, Jakub Moder and Adam Webster are also missing through injury, but the team did not pick up any fresh issues against Charlton last time out.
There will be changes from the EFL Cup fixture, with Leandro Trossard, Pervis Estupinan and Kaoru Mitoma expected to come back into the side for the Premier League contest with Southampton.
Possible starting lineup:
Data will be available at kick off time or sooner.
Southampton = 21.2%
Draw = 25.0%
Brighton = 53.8%
Southampton 0-1 Brighton
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