Vice-captain Courtney Lawes will miss the rest of England’s Six Nations campaign with a shoulder injury.
Meanwhile, fly-half Marcus Smith has been retained in the 27-man squad, with George Ford going back to Sale.
It means Smith is set to feature against France on Saturday despite being released from camp last week.
Read Also
Ford’s inclusion over Smith during the fallow week suggested the former would be preferred in the matchday squad to face France.
“We’ve got three world-class 10s, and we felt it was the right thing for Marcus to get some minutes,” Sinfield told BBC Sport.
“We all feel it was the right thing for Marcus to go back and play, and he was outstanding, wasn’t he?
Sinfield says Ford has been “outstanding” in camp and had been in contention to face France after a long lay-off with an Achilles tendon injury.
“But we can’t keep all three here, one of them needs to go away and play, and we decided this week it was going to be George.”
Sinfield also confirmed Lawes would play no further part in the Championship after suffering a shoulder injury in the gym.
“We are waiting for a full report, but unfortunately he will miss the rest of the campaign for us,” Sinfield said.
England squad
Forwards: Ollie Chessum, Dan Cole, Ben Curry, Alex Dombrandt, Ben Earl, Ellis Genge, Jamie George, Nick Isiekwe, Maro Itoje, Lewis Ludlam, David Ribbans, Kyle Sinckler, Mako Vunipola, Jack Walker, Jack Willis.
Backs: Henry Arundell, Owen Farrell, Ollie Lawrence, Max Malins, Joe Marchant, Alex Mitchell, Henry Slade, Marcus Smith, Freddie Steward, Manu Tuilagi, Jack van Poortvliet, Anthony Watson.
